Transformation zone location and intraepithelial neoplasia of the cervix uteri

High intraepithelial expression of estrogen and progesterone receptors in the transformation zone of the uterine cervix.

OBJECTIVE Because sex hormones may be involved in tumor initiation and progression, we analyzed the presence of hormone receptors in the transformation zone of the uterine cervix where the majority of human papillomavirus infections and associated (pre)neoplastic lesions develop. STUDY DESIGN By using 23 total hysterectomy samples from young women who underwent surgery for noncervical benign ...

Large loop excision of the transformation zone and cervical intraepithelial neoplasia: a 22-year experience.

AIM To review the 22-year experience of the use of large loop excision of the transformation zone (LLETZ) for the treatment of cervical intraepithelial neoplasia (CIN). MATERIALS AND METHODS DESIGN Retrospective observational study. SETTING University Hospital of Ioannina, Greece. PERIOD January 1989 until December 2011. POPULATION Women undergoing excisional treatment with LLETZ for...

Frequency of cervical intraepithelial neoplasia following large loop excision of the transformation zone.

AIM To determine the frequency of cervical intraepithelial neoplasia (CIN) following large loop excision of the transformation zone of the cervix (LLETZ) according to grade and completeness of excision of CIN. METHODS A retrospective study of 669 patients who had LLETZ biopsies showing CIN 1, 2, or 3. The patients were subdivided according to the grade and completeness of excision of CIN. The...

Cancer of the cervix uteri.

The cervix is the lower aspect of the uterus. It is roughly cylindrical in shape, projects through the superior-anterior vaginal wall, and communicates with the vagina through the endocervical canal, which terminates in the external os located at the top of the vagina. Cancer of the cervix may originate from the mucosa of the surface of the cervix or from within the canal. Carcinoma of the uter...

Atresia of the Vagina and Cervix Uteri